Microbial Toxins and Venoms, Clinical Toxicology
The Journal of Clinical Toxicology (JCT) is Scholarly Open Access journal that deals with the study of xenobiotics and alsostudy toxic effects of agents (drugs) whose purpose is to ameliorate or prevent a disease. The journal addresses both scientific research and clinical advances in clinical toxicology. This free clinical journal provides an open access platform for researcher’s work in clinical toxicology in hospitals, academia, government or industrial sectors.
This Scientific journal includes a wide range of fields in its discipline to create a platform for the authors to make their contribution towards the journal and the editorial office promises a peer review process for the submitted manuscripts for the quality of publishing. The journal is using Editorial Tracking System for quality peer-review process. Editorial Tracking is an online manuscript submission, review and Managing systems. Review processing is performed by the editorial board members of Journal of Clinical Toxicology or outside experts; at least two independent reviewers approval followed by editor approval is required for acceptance of any citable manuscript. Journal of Clinical Toxicology aims to publish most complete and reliable source of information on the discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in all areas of the field and making them freely available through online without any restrictions or any other subscriptions to researchers worldwide.Excellent contributions are welcome to receive high impact factor for this scholarly journal.
This ‘Research Topic’ deals with the various ‘Venoms, Animal and Microbial Toxins’. It is devoted to the toxins/molecules (and derivatives thereof) from marine and non-marine animal venoms, plants/algae, and microbes. The ‘Research Topic’mainly focuses on the structural characteristics, structure-function relationship, and pharmacology of toxins. It also covers the natural or non-natural/synthetic toxic substances of various origins, with some potential as lethal biological weapons (bioterrorism).
Venomous animals (e.g. scorpions, snakes, sea anemones, cone snails, worms, wasps, lizards and frogs) and microbes (bacteria, viruses and fungi) are producing more or less potent and specific toxins to neutralize or kill their preys or hosts. Basically, these toxins are of various nature and size (proteins, peptides, organic compounds), and can act with a variety of modes of action depending on their origins (animal venoms, bacteria, viruses, fungi) and targets. In venoms, most of the animal toxins are acting on ion channels (sodium, potassium, calcium and chloride channels) or enzymes, but they can also act on neurotransmitter release thus altering the nervous transmission, similar to some of the lethal microbial toxins (especially from bacteria). Because of their wide range of bioactivities, many research groups worldwide are investigating the structural and functional properties of these particular compounds. Interestingly, some of the toxins can be developed as candidate chemotherapeutic drugs to treat pain, cancer, microbial infections, neurological and immune disorders (e.g. conopeptides, ion channel-acting animal toxins) whereas others as potential biological weapons (e.g. anthrax, ricin, conotoxins).
This Research Topic is mainly centered on the structural and functional properties of the animal and microbial toxins, and targets thereof. Indeed, it appears crucial to collect the more information on the structural features/characteristics of toxins and their derivatives, as well as on their various modes of action, at a molecular level, to a better understanding of these compounds. The non-natural toxic molecules are also considered. An ‘in-depth’ knowledge of the toxins (and derivatives) will certainly open the way to the design of new drugs and appropriate antitoxin countermeasures, which would be the ultimate goal of the Research Topic.
Journal of Clinical Toxicology
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